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Research Groups

Featured Publications

A second update on mapping the human genetic architecture of COVID-19

Authors: Masahiro Kanai, Shea J Andrews, Mattia Cordioli, Christine Stevens, Benjamin M Neale, Mark Daly, Andrea Ganna, Gita A Pathak, Akiko Iwasaki, Juha Karjalainen, Juha Mehtonen, Matti Pirinen, Karolina Chwialkowska, Amy Trankiem, Mary K Balaconis, Kumar Veera2024

Journal: Nature

Doi: https://doi.org/10.1038/s41586-021-03767-x

Advancements and Challenges in Aptamer-Based Therapeutics and Diagnostics Across Diverse Medical Domains: A Comprehensive Review

Authors: Talal aburjai Ahmed S.A. Ali Agha, Walhan Alshaer2024

Journal: Jordan Journal of Pharmaceuticals Sciences (JJPS)

Doi: https://doi.org/10.35516/jjps.v17i2.1895

Downregulation of STAT3, β-Catenin, and Notch-1 by Single and Combinations of siRNA Treatment Enhance Chemosensitivity of Wild Type and Doxorubicin Resistant MCF7 Breast Cancer Cells to Doxorubicin

Authors: Walhan Alshaer, Dana A. Alqudah, Suha Wehaibi, Duaa Abuarqoub, Malek Zihlif, Ma’mon M. Hatmal, and Abdalla Awidi2024

Journal: International Journal of Molecular Sciences

Doi: https://www.mdpi.com/1422-0067/20/15/3696

Doxorubicin conjugates: a practical approach for its cardiotoxicity alleviation

Authors: Abed Alqader Ibrahim, Hamdi Nsairat, Mazen Al-Sulaibi, Mohamed El-Tanani, Areej M Jaber, Zainab Lafi, Rahmeh Barakat, Duaa Azmi Abuarqoub, Ismail Sami Mahmoud, Sherine O Obare, Alaa A A Aljabali, Alaaldin M Alkilany, Walhan Alshaer2024

Journal: Expert Opinion on Drug Delivery

Doi: https://pubmed.ncbi.nlm.nih.gov/38623735/

Dual stimuli-responsive polymeric nanoparticles combining soluplus and chitosan for enhanced breast cancer targeting

Authors: Shrouq Twal, Nisrein Jaber, Mayyas Al-Remawi, Islam Hamad, Faisal Al-Akayleh, Walhan Alshaer2024

Journal: RSC Advances

Doi: https://doi.org/10.1039/D3RA08074A

Encapsulation of gingerol into nanoliposomes: Evaluation of in vitro anti-inflammatory and anti-cancer activity

Authors: Fatima Alshaikh, Ali Al-Samydai, Reem Issa, Walhan Alshaer, Moath Alqaraleh, Lidia K. Al-Halaseh, Alaa Alsanabrah, Bayan Y. Ghanim, Khaldun M. Al Azzam, Nidal A. Qinna2024

Journal: Biomedical Chromatography

Doi: https://doi.org/10.1002/bmc.5899

Enhancing chemosensitivity of PANC1 pancreatic cancer cells to gemcitabine using ANGTPL4, Notch1 and NF-κβ1 siRNAs

Authors: Abdulfattah Al-Kadash, Walhan Alshaer, Ismail Sami Mahmoud, Suha Wehaibi, Malek Zihlif2024

Journal: Future Science OA

Doi: https://doi.org/10.2144/fsoa-2023-0145

Evaluation of Bis-biphenyl Salicylaldehyde Schiff Base Derivatives for Alpha-Glucosidase Inhibition: Anticancerous Activity and Molecular Modelling Studies

Authors: Majd M. Alsaleh Taher S. Ababneh , Taghreed M. Jazzazi, Mazhar Al Zoubi, Tareq. M. Alshboul, Walhan Alshaer, Abd Al-Aziz A. Abu-Saleh, Mansour H. Almatarneh, Mohammed-Jamal A. Shammout, Iyad Y. Natsheh2024

Journal: Jordan Journal of Biological Sciences

Doi: https://doi.org/10.54319/jjbs/170212

Exploring the Phytoconstituents, Differential Pharmacology, and Interaction with Empagliflozin of Olea europaea Leaves Extracts

Authors: Zinah Kadhim Saeed, Ali Mahmoud Al-Samydai, Moath Alqaraleh, Nidal Adel Qinna, Bayan Yousef Ghanim, Amal Mayyas, Deniz Al-Tawalbeh, Shrouq Taiseer Alsotari, Walhan Alshaer, Farah Al-Mamoori, Lidia Kamal Al-Halaseh2024

Journal: Ind. J. Pharm. Edu. Res.

Doi: https://ijper.org/article/doi/5819/#:~:text=DOI%3A,ijper.58.3s.100

Formulation Optimization of Lyophilized Aptamer-Gold Nanoparticles: Maintained Colloidal Stability and Cellular Uptake

Authors: Dalya Saidi, Marya Obeidat, Shrouq Alsotari, Abed-Alqader Ibrahim, Rula Al-Buqain, Suha Wehaibi, Dana A. Alqudah, Hamdi Nsairat, Walhan Alshaer, Alaaldin M. Alkilany2024

Journal: Heliyon

Doi: https://doi.org/10.1016/j.heliyon.2024.e30743

Gemcitabine-loaded niosomes: Optimization, characterization, and in vitro efficacy against invasive malignancies

Authors: Nowar Alsarayreh, Sharif Abdelghany, Dana Alqudah, Duaa Abuarqoub, Walhan Alshaer2024

Journal: Journal of Drug Delivery Science and Technology

Doi: https://doi.org/10.1016/j.jddst.2024.105617

Hyaluronic Acid – Coated Niosomes for Curcumin Targeted Delivery into Breast Cancer Cells

Authors: Zahraa M. Al Zubaidi, Hamdi Nsairat, Naeem M. Shalan, Leena Al-Asfoor, Dana A. Alqudah, Mairvat Mrahleh, Walhan Alshaer2024

Journal: ChemistrySelect

Doi: https://doi.org/10.1002/slct.202304649

Liposome bilayer stability: Emphasis on cholesterol and its alternatives

Authors: Hamdi Nsairat, Abed Alqader Ibrahim, Areej M Jaber, Sharif Abdelghany, Randa Atwan, Naeem Shalan, Hiba Abdelnabi, Fadwa Odeh, Mohamed El-Tanani, Walhan Alshaer2024

Journal: Journal of Liposome Research

Doi: https://doi.org/10.1080/08982104.2023.2226216

pH-responsive LBL coated silica nanocarriers for controlled release of chlorhexidine

Authors: Yazan Al Thaher , Sharif Abdelghany , Samer R. Abulateefeh 2024

Journal: Colloids and Surfaces A: Physicochemical and Engineering Aspects

Doi: https://doi.org/10.1016/j.colsurfa.2023.132671

Research Trend in The Inhibition of Transient Receptor Potential Vanilloid 1 (TRPV1): Bibliometric Analysis and Visualization

Authors: Shereen M. Aleidi, Amani A. Harb, Lina A. Dahabiyeh, Montaha AL-Iede, Islam Hamad, Walhan Alshaer, Ihab M. Almasri, Yasser Bustanji2024

Journal: J Appl Pharm Sci

Doi: http://doi.org/10.7324/JAPS.2024.188749

Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic anticancer leads

Authors: Mohammed M. Al-Mahadeen, Areej M. Jaber, Jalal A. Zahra, Mustafa M. El-Abadelah, Walhan Alshaer & Mutasem O. Taha2024

Journal: Medicinal Chemistry Research

Doi: https://doi.org/10.1007/s00044-024-03229-9

Synthesis, characterization, and wound healing activity of alginate-based polymeric nanoparticles loaded with stingless bee honey

Authors: Mohammad A.I. Al-Hatamleh, Walhan Alshaer, Ma’mon M. Hatmal, Abed Alqader Ibrahim, Anthony L. Dellinger, Hamdi Nsairat, Maram Abdaljaleel, Mohd Zulkifli Mustafa, Rohimah Mohamud2024

Journal: Biocatalysis and Agricultural Biotechnology

Doi: https://doi.org/10.1016/j.bcab.2024.103329

1,4-Naphthoquinone Induces FcRn Protein Expression and Albumin Recycling in Human THP-1 Cells

Authors: Ezaldeen Ismael Esawi, Ismail Sami Mahmoud, Mohammad Salah Abdullah, Duaa Azmi Abuarqoub, Mamoun Ahmad Ahram, Walhan Mohammad Alshaer2023

Journal: ACS Omega

Doi: https://pubs.acs.org/doi/full/10.1021/acsomega.3c01678

Aptasensors: employing molecular probes for precise medical diagnostics and drug monitoring

Authors: Zainab Lafi, Lobna Gharaibeh, Hamdi Nsairat, Nisreen Asha, Walhan Alshaer2023

Journal: Bioanalysis

Doi: https://doi.org/10.4155/bio-2023-0141

Biological Performance of Primary Dental Pulp Stem Cells Treated with Gold Nanoparticles

Authors: Duaa Abuarqoub, Nouf Mahmoud, Walhan Alshaer, Marwa Mohammad, Abed Alqader Ibrahim, Mairvat Al-Mrahleh, Mohammad Alnatour, Dana A Alqudah, Ezaldeen Esawi, Abdalla Awidi2023

Journal: Biomedicines

Doi: https://doi.org/10.3390/biomedicines11092490

Clinical use and future perspective of aptamers

Authors: Ezaldeen Esawi, Hamdi Nsairat, Ismail Sami Mahmoud, Zainab Lafi, Abdulfattah Al-Kadash, Bayan Abu Al-Ragheb, Said I Ismail, Walhan Alhaer2023

Journal: Aptamers Engineered Nanocarriers for Cancer Therapy

Doi: https://doi.org/10.1016/B978-0-323-85881-6.00013-0

Cosmeceutical formulations of pro-vitamin E phosphate: In-vitro release testing and dermal penetration into excised human skin

Authors: Mais M Saleh, Raghad M Abuhamdan, Walhan Alshaer, Marzouq Amarin, Hiba Abdelnabi, Maram Abdaljaleel, Kholoud Friehat, Salah Aljamal, Samer M Najjar, Saja H Hamed2023

Journal: International Journal of Pharmaceutics

Doi: https://doi.org/10.1016/j.ijpharm.2023.122781

Curcumin-loaded γ -cyclodextrin-grafted hyaluronic acid nanoassimblies: In vitro investigation of anti-proliferative, wound healing, and anti-inflammatory potential

Authors: Fedaa Adaileh, Walhan Alshaer, Hamdi Nsairat, Dana A. Alqudah, Suha Wehaibi, Fadwa Daoud, Rula Al-Buqain, Shrouq Alsotari, Abeer Al Bawab, Fadwa Odeh2023

Journal: Journal of Drug Delivery Science and Technology

Doi: https://doi.org/10.1016/j.jddst.2023.104886

Development and validation of Ran as a prognostic marker in stage I and stage II primary breast cancer

Authors: Mohamed El-Tanani, Angela Platt-Higgins, Hamdi Nsairat, Ismail I. Matalka, Khaled Abdul-Aziz Ahmed, Shu-Dong Zhang, Walhan Alshaer, Abdalla Awidi, Kyle B. Matchett, Alaa A. Aljabali, Vijay Mishra, Ángel Serrano-Aroca, Murtaza M. Tambuwala, Philip S. Rudla2023

Journal: Life Sciences

Doi: https://doi.org/10.1016/j.lfs.2023.121964

Development and validation of reversed-phase-HPLC method for simultaneous quantification of fulvestrant and disulfiram in liposomes

Authors: Hamdi Nsairat, Walhan Alshaer, Zainab Lafi, Somaya Ahmad, Alaa Al-Sanabrah, Mohamed El-Tanani2023

Journal: Bioanalysis

Doi: https://doi.org/10.4155/bio-2023-0137

Development of Pegylated Nano-Phytosome Formulation with Oleuropein and Rutin to Compare Anti-Colonic Cancer Activity with Olea Europaea Leaves Extract

Authors: Tabarek H Mahmood, Hamdi Nsairat, Ali Al-Samydai, Mazen Al Sulaibi, Moath Alqaraleh, Anas Ibrahim Abed, Naeem Shalan, Alaa Alsanabrah, Shrouq Taiseer Alsotari, Walhan Alshaer2023

Journal: Chemistry & Biodiversity

Doi: https://doi.org/10.1002/cbdv.202300534

Discovery of new STAT3 inhibitors as anticancer agents using ligand-receptor contact fingerprints and docking-augmented machine learning

Authors: Nour Jamal Jaradat, Walhan Alshaer, Mamon Hatmal, Mutasem Omar Taha2023

Journal: RSC Advances

Doi: https://doi.org/10.1039/D2RA07007C

Echinomycin: A Journey of Challenges

Authors: Zainab Lafi, Walhan Alshaer, M Hatmal Ma’mon, Malek A Zihlif, Nisreen Y Asha, Hiba Abdelnabi, Abdullah Awidi2023

Journal: JJPS

Doi: https://doi.org/10.35516/jjps.v16i3.918

Formulating co-loaded nanoliposomes with gallic acid and quercetin for enhanced cancer therapy

Authors: Ali Al-Samydai, Moath Al Qaraleh, Khaldun M. Al Azzam, Amal Mayyas, Hamdi Nsairat, Maha N. Abu Hajleh, Lidia K. Al-Halaseh, Nehaya Al-Karablieh, Amal Akour, Fatima Alshaik, Walhan Alshaer2023

Journal: Heliyon

Doi: https://doi.org/10.1016/j.heliyon.2023.e17267

Impact of Nanotechnology on the Oral Delivery of Phyto-bioactive Compounds

Authors: Hamdi Nsairat, Zainab Lafi, Mazen Al-Sulaibi, Lobna Gharaibeh, Walhan Alshaer2023

Journal: Food Chemistry

Doi: https://doi.org/10.1016/j.foodchem.2023.136438

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Authors: Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobbs, Matthew Moll, Wonji Kim, Ruth Tal-Singer, Per Bakke, Katherine A Fawcett, Catherine J2023

Journal: Nature genetics

Doi: https://www.nature.com/articles/s41588-023-01314-0

Needle phobia among adult jordanians: General awareness, prevalence; and exploring microneedles as a promising solution

Authors: S Abdelghany, S Al-Muhaissen, YA Thaher, M Melhem, M Fashho, O Alfuqaha, M Saleh2023

Journal: Plos one

Doi: https://doi.org/10.1371/journal.pone.0291807

PEGylated nanoassemblies composed of edelfosine and fulvestrant drugs: In vitro antiproliferative effect against breast cancer cells

Authors: Hamdi Nsairat, Mazen Al-Sulaibi, Walhan Alshaer2023

Journal: Journal of Drug Delivery Science and Technology

Doi: https://doi.org/10.1016/j.jddst.2023.104612

Phytosomes: a modernistic approach to the delivery of herbal drugs

Authors: Hamdi Nsairat, Dima Khater, Fadwa Odeh, Areej M. Jaber, Mazen A.M. Al Sulaibi, Walhan Alshaer, Abeer Al Bawab, Mohammad S. Mubarak2023

Journal: Advanced and Modern Approaches for Drug Delivery

Doi: https://doi.org/10.1016/B978-0-323-91668-4.00029-0

Preparation, characterization and wound-healing effect of PEGylated nanoliposomes loaded with oleuropein

Authors: Rand Alquraishi, Ali Al-samydai, Khaldun M. Al Azzam, Moath Alqaraleh, Lidia Al-Halaseh, Alaa Sanabrah, Maha N. Abu Hajleh, Arwa Al Khatib, Walhan Alsaher, El-Sayed Negim, Khaled Khleifat2023

Journal: Biomedical Chromatography

Doi: https://doi.org/10.1002/bmc.5716

Preparation, Characterization, and Anticancer Activity of PEGylated Nano liposomal Loaded with Rutin against Human Carcinoma Cells (HT-29)

Authors: Noorin Manhal Al-Ekaid, Ali M. Al-Samydai, Ibrahim Al-deeb, Hamdi Nsairat, Khaled Khleifat, Walhan Alshaer2023

Journal: Chemistry & Biodiversity

Doi: https://doi.org/10.1002/cbdv.202301167

Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors (vol 10, 1078163, 2022)

Authors: Ihab Shawish, Mohamed SS Nafie, Assem Barakat, Ali Aldalbahi, Hessa HH Al-Rasheed, M Ali, Walhan Alshaer, Mazhar Al Zoubi, Samha Al Ayoubi, Beatriz GG de la Torre, Fernando Albericio, Ayman El-Faham2023

Journal: FRONTIERS IN CHEMISTRY

Doi: https://doi.org/10.3389/fchem.2022.1078163

Quality by Design Approach in Liposomal Formulations: Robust Product Development

Authors: Walhan Alshaer, Hamdi Nsairat, Zainab Lafi, Omar M. Hourani, Abdulfattah Al-Kadash, Ezaldeen Esawi, Alaaldin M. Alkilany2023

Journal: Molecules

Doi: https://doi.org/10.3390/molecules28010010

Recent Advances in Using Liposomes for Delivery of Nucleic Acid-Based Therapeutics

Authors: Hamdi Nsairat, Walhan AlShaer, Fadwa Odeh, Ezzaldeen Essawi, Dima Khater, Abeer Al Bawab, Mohamed El-Tanani, Abdalla Awidi, Mohammad S. Mubarak2023

Journal: OpenNano

Doi: https://doi.org/10.1016/j.onano.2023.100132

Role of mammalian target of rapamycin (mTOR) signalling in oncogenesis

Authors: Mohamed El-Tanani, Hamdi Nsairat, Alaa A. Aljabali, Ángel Serrano-Aroca-Angel, Vijay Mishra, Yachana Mishra, Gowhar A. Naikoo, Walhan Alshaer, Murtaza M. Tambuwala2023

Journal: Life Sciences

Doi: https://doi.org/10.1016/j.lfs.2023.121662

Synergistic combination of doxorubicin with hydralazine and disulfiram against MCF-7 breast cancer cell line

Authors: Zainab Lafi, Walhan Alshaer, Lobna Gharaibeh, Dana A Alqudah, Baidaa AlQuaissi, Banan Bashaireh, Abed Alqader Ibrahim2023

Journal: Plos one

Doi: https://doi.org/10.1371/journal.pone.0291981

Telmisartan Enhances the Accumulation of Doxorubicin as a Combination Therapy for the Management of Triple Negative Breast Cancer

Authors: Wala’a Al. Safadi, Belal Omar Al-Najjar, MoathAlqaraleh, Ibrahim Abed Anas, Walhan Alshaer, Dana Alqudah, Fadwa Daoud, Razan Mohammad Obeidat, Obada Abdulmalek Sibai, Zainab Zaki Zakaraya2023

Journal: Jordan Journal of Biological Sciences

Doi: https://doi.org/10.54319/jjbs/160315

The editorial on the Research Topic: Anti-Cancer Drug Delivery: Lipid-Based Nanoparticles

Authors: Alaaldin Alkilany, Amit Kunwar, Jyotsnendu Giri, Walhan Alshaer, Abdelbary Elhissi2023

Journal: Frontiers in Oncology

Doi: https://doi.org/10.3389/fonc.2023.1248272

Understanding the challenges to COVID-19 vaccines and treatment options, herd immunity and probability of reinfection

Authors: Mohammad A.I. Al-Hatamleh, Mai Abdel Haleem Abusalah, Ma'mon M. Hatmal, Walhan Alshaer, Suhana Ahmad, Manali Haniti Mohd-Zahid, Engku Nur Syafirah E.A. Rahman, Chan YeanYean, Iskandar Z. Alias, VukUskoković, RohimahMohamud2023

Journal: Journal of Taibah University Medical Sciences

Doi: https://doi.org/10.1016/j.jtumed.2022.11.007

Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades

Authors: Ihab Shawish, Assem Barakat, Ali Aldalbahi, Walhan Alshaer, Fadwa Daoud, Dana A. Alqudah, Mazhar Al Zoubi, Ma’mon M. Hatmal, Mohamed S. Nafie, Matti Haukka, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio, Ayman El-Faham2022

Journal: Pharmaceutics

Doi: https://doi.org/10.3390/pharmaceutics14081558

Applications of Alginate-Based Nanomaterials in Enhancing the Therapeutic Effects of Bee Products

Authors: Mohammad AI Al-Hatamleh, Walhan Alshaer, Ma'mon M Hatmal, Lidawani Lambuk, Naveed Ahmed, Mohd Zulkifli Mustafa, Siew Chun Low, Juhana Jaafar, Khalid Ferji, Jean-Luc Six, Vuk Uskokovic, Rohimah Mohamud2022

Journal: Frontiers in Molecular Biosciences

Doi: https://doi.org/10.3389/fmolb.2022.865833

Aptamers in Theranostic Bionanomaterials

Authors: Hamdi Nsairat, Walhan Alshaer, Ismail Sami Mahmoud, Mohammad A Ismail, Ezaldeen Esawi, Shrouq Alsotari, Said I. Ismail2022

Journal: Bionanotechnology: Next-Generation Therapeutic Tools

Doi: https://www.eurekaselect.com/chapter/17168#:~:text=DOI%3A%2010.2174/9789815051278122010008

Biosynthesis of gold nanoparticles using leaf extract of Dittrichia viscosa and in vivo assessment of its anti-diabetic efficacy

Authors: Sanaa Ayyoub, Bahaa Al-Trad, Alaa A. A. Aljabali, Walhan Alshaer, Mazhar Al Zoubi, Sahar Omari, Diaa Fayyad, Murtaza M. Tambuwala2022

Journal: Drug Delivery and Translational Research

Doi: https://link.springer.com/article/10.1007/s13346-022-01163-0

Cinnamaldehyde–cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity

Authors: Bayan Al Tbakhi, Hamdi Nsairat, Walhan Alshaer, Abdulfattah Al-Kadash, Wissam Helal, Lubna Alrawashdeh, Anthony Day, Khaleel I. Assaf, Rola Hassouneh, Fadwa Odeh, Abeer Al Bawab2022

Journal: RSC Advances

Doi: https://doi.org/10.1039/D2RA00044J

Ciprofloxacin-loaded dissolving polymeric microneedles as a potential therapeutic for the treatment of S. aureus skin infections

Authors: Sharif Abdelghany, Walhan Alshaer, Yazan Al Thaher, Maram Al Fawares, Amal G. Al-Bakri, Saja Zuriekat, Randa SH. Mansour2022

Journal: Beilstein Journal of Nanotechnology

Doi: https://doi.org/10.3762/bjnano.13.43

Ciprofloxacin-loaded dissolving polymeric microneedles as a potential therapeutic for the treatment of S. aureus skin infections

Authors: Sharif Abdelghany, Walhan Alshaer , Yazan Al Thaher , Maram Al Fawares , Amal G Al-Bakri , Saja Zuriekat , Randa Sh Mansour 2022

Journal: Beilstein J Nanotechnol .

Doi: https://doi.org/10.3762/bjnano.13.43

Computational and experimental characterizations of annealed Cu2ZnSnS4 thin films

Authors: Ahmad A Ahmad, AB Migdadi, Ahmad M Alsaad, IA Qattan, Qais M Al-Bataineh, Ahmad Telfah2022

Journal: Heliyon

Doi: https://doi.org/10.1016/j.heliyon.2021.e08683

Effects of cyclic acute and chronic hypoxia on the expression levels of metabolism related genes in a pancreatic cancer cell line

Authors: Nour M. Obeidat, Malek A. Zihlif, Dana A. Alqudah, Walhan Alshaer, Moath Alqaraleh, Shtaywy S. Abdalla2022

Journal: Biomedical Reports

Doi: https://doi.org/10.3892/br.2022.1564

Immunomodulatory Properties of Human Breast Milk: MicroRNA Contents and Potential Epigenetic Effects

Authors: Ma’mon M. Hatmal, Mohammad A. I. Al-Hatamleh, Amin N. Olaimat, Walhan Alshaer, Hanan Hasan, Khaled A. Albakri, Enas Alkhafaji, Nada N. Issa, Murad A. Al-Holy, Salim M. Abderrahman, Atiyeh M. Abdallah, Rohimah Mohamud2022

Journal: Biomedicines

Doi: https://doi.org/10.3390/biomedicines10061219

Liposomes: Structure, composition, types, and clinical applications

Authors: Hamdi Nsairat, Dima Khater, Usama Sayed, Fadwa Odeh, Abeer Al Bawab, Walhan Alshaer2022

Journal: Heliyon

Doi: https://doi.org/10.1016/j.heliyon.2022.e09394

Molecular and cellular effects of gold nanoparticles treatment in experimental diabetic myopathy

Authors: Aseel Al-Shwaheen, Alaa A. A. Aljabali, Ghada Alomari, Mazhar Al Zoubi, Walhan Alshaer, Bahaa Al-Trad, Murtaza M. Tambuwala2022

Journal: Heliyon

Doi: https://doi.org/10.1016/j.heliyon.2022.e10358

Multifunctional nanoparticles recruiting hyaluronic acid ligand and polyplexes containing low molecular weight protamine and ATP-Sensitive DNA motif for doxorubicin delivery

Authors: Hafsa Al-Azzawi, Walhan Alshaer, Ezaldeen Esawi, Zainab Lafi, Duaa Abuarqoub, Rand Zaza, Manar Zraikat, Abdelkader Battah, Abdalla Awidi2022

Journal: Journal of Drug Delivery Science and Technology

Doi: https://doi.org/10.1016/j.jddst.2022.103169

Noncovalent functionalization of carbon nanotubes as a scaffold for tissue engineering

Authors: Mohyeddin Assali, Naim Kittana, Sahar Alhaj-Qasem, Muna Hajjyahya, Hanood Abu-Rass, Walhan Alshaer, Rula Al-Buqain2022

Journal: Scientific Reports

Doi: https://www.nature.com/articles/s41598-022-16247-7

Preparation, characterization, and biological activity study of thymoquinone-cucurbit[7]uril inclusion complex

Authors: Lubna Alrawashdeh, Khaleel I. Assaf, Walhan Alshaer, Fadwa Odeh, Suhair A. Bani-Atta2022

Journal: RSC Advances

Doi: https://pubs.rsc.org/en/content/articlelanding/2022/ra/d1ra08460g#:~:text=DOI,org/10.1039/D1RA08460G

Preparation, Characterization, Wound Healing, and Cytotoxicity Assay of PEGylated Nanophytosomes Loaded with 6-Gingerol

Authors: Ali Al-Samydai, Moath Al Qaraleh, Walhan Alshaer, Lidia K. Al-Halaseh, Reem Issa, Fatima Alshaikh, Aseel Abu-Rumman, Hayat Al-Ali, Emad A. S. Al-Dujaili2022

Journal: Nutrients

Doi: https://doi.org/10.3390/nu14235170

Research Article The Immunomodulatory and Regenerative Effect of Biodentine™ on Human THP-1 Cells and Dental Pulp Stem Cells: In Vitro Study

Authors: Duaa Abuarqoub, Nazneen Aslam, Rand Zaza, Hanan Jafar, Suzan Zalloum, Renata Atoom, Walhan Alshaer, Mairvat Al-Mrahleh, Abdalla Awidi2022

Journal: BioMed Research International

Doi: https://doi.org/10.1155/2022/2656784

Structure, composition, types, and clinical applications

Authors: Hamdi Nsairata ∙ Dima Khaterb ∙ Usama Sayedc ∙ Fadwa Odehd ∙ Abeer Al Bawabd,e ∙ Walhan Alshaer2022

Journal: European journal of pharmacology

Doi: https://www.cell.com/heliyon/fulltext/S2405-8440(22)00682-X

Synthesis of Mono-Amino Substituted γ-CD: Host–Guest Complexation and In Vitro Cytotoxicity Investigation

Authors: Fadwa Odeh, Fedaa Adaileh, Walhan Alshaer, Hamdi Nsairat, Dana A. Alqudah, Areej M. Jaber, Abeer Al Bawab2022

Journal: Molecules

Doi: https://doi.org/10.3390/molecules27051683

Synthesis, Characterization, and Assessment of Anti-Cancer Potential of ZnO Nanoparticles in an In Vitro Model of Breast Cancer

Authors: Alaa A. A. Aljabali, Mohammad A. Obeid, Hamid A. Bakshi, Walhan Alshaer, Raed M. Ennab, Bahaa Al-Trad, Wesam Al Khateeb, Khalid M. Al-Batayneh, Abdulfattah Al-Kadash, Shrouq Alsotari, Hamdi Nsairat, Murtaza M. Tambuwala2022

Journal: Molecules

Doi: https://doi.org/10.3390/molecules27061827

Synthesis, Characterization, Computational and Biological Activity of Some Schiff Bases and Their Fe, Cu and Zn Complexes

Authors: Tareq M. A. Al-Shboul, Mohammad El-khateeb, Zaid H. Obeidat, Taher S. Ababneh, Suha S. Al-Tarawneh, Mazhar S. Al Zoubi, Walhan Alshaer, Anas Abu Seni, Taqwa Qasem, Hayato Moriyama, Yukihiro Yoshida, Hiroshi Kitagawa, Taghreed M. A. Jazzazi2022

Journal: Inorganics

Doi: https://doi.org/10.3390/inorganics10080112

The Immunomodulatory and Regenerative Effect of Biodentine™ on Human THP-1 Cells and Dental Pulp Stem Cells: In Vitro Study

Authors: Duaa Abuarqoub, Nazneen Aslam, Rand Zaza, Hanan Jafar, Suzan Zalloum, Renata Atoom, Walhan Alshaer, Mairvat Al-Mrahleh, Abdalla Awidi2022

Journal: BioMed Research International

Doi: https://doi.org/10.1155/2022/2656784

1,4-Napthoquinone Is a Potent Inhibitor of IRAK1 Kinases and the Production of Inflammatory Cytokines in THP-1 Differentiated Macrophages

Authors: Ismail Sami Mahmoud, Ma’mon M. Hatmal, Duaa Abuarqoub, Ezaldeen Esawi, Hiba Zalloum, Suha Wehaibi, Hamdi Nsairat, Walhan Alshaer2021

Journal: ACS Omega

Doi: https://pubs.acs.org/doi/full/10.1021/acsomega.1c03081

Alleviation of diabetic nephropathy by zinc oxide nanoparticles in streptozotocin‐induced type 1 diabetes in rats

Authors: Ghada Alomari, Bahaa Al‐ Trad, Salehhuddin Hamdan, Alaa A. A. Aljabali, Mazhar Salim Al Zoubi, Khalid Al‐ Batanyeh, Janti Qar, Gregory J. Eaton, Almuthanna K. Alkaraki, Walhan Alshaer, Saja Haifawi, Khairunadwa Jemon, Dinesh Kumar Chellappan, Kamal Dua, M2021

Journal: IET Nanobiotechnology

Doi: https://doi.org/10.1049/nbt2.12026

An In Vitro Comparison of Anti-Tumoral Potential of Wharton’s Jelly and Bone Marrow Mesenchymal Stem Cells Exhibited by Cell Cycle Arrest in Glioma Cells (U87MG)

Authors: Nazneen Aslam, Elham Abusharieh, Duaa Abuarqoub, Dana Alhattab, Hanan Jafar, Walhan Alshaer, Razan J. MasadAbdalla S. Awidi2021

Journal: Pathology and Oncology Research

Doi: https://pubmed.ncbi.nlm.nih.gov/34257532/#:~:text=doi%3A%2010.3389/pore.2021.584710.

Anticancer Cardenolides from the aerial parts of Calortopis procera

Authors: Nuha Sweidan, Ezaldeen Esawi, Mohammad Ismail, Walhan Alshaer2021

Journal: Zeitschrift für Naturforschung C

Doi: https://www.degruyter.com/document/doi/10.1515/znc-2020-0281/html

Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in vitro

Authors: Nazneen Aslam, Elham Abusharieh, Duaa Abuarqoub, Dema Ali, Dana Al-Hattab, Suha Wehaibi, Ban Al-Kurdi, Fatima Jamali, Walhan Alshaer, Hanan Jafar, Abdalla S Awidi2021

Journal: Molecular Therapy-Oncolytics

Doi: https://pubmed.ncbi.nlm.nih.gov/33575478/#:~:text=doi%3A%2010.1016/j.omto.2020.11.005.

Aptamer-Aptamer Chimera for Targeted Delivery and ATP-Responsive Release of Doxorubicin into Cancer Cells

Authors: E. Esawi, W. Alshaer, I.S. Mahmoud, D.A. Alqudah, B. Azab, A Awidi2021

Journal: International Journal of Molecular Sciences

Doi: https://doi.org/10.3390/ijms222312940

Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells

Authors: Zainab Lafia, Walhan Alshaer, Ma'mon M. Hatmal, Malek Zihlif, Dana Alqudah, Hamdi Nsairat, Hanan Azzam, Talal Aburjai, Yasser Bustanji, Abdalla Awidi2021

Journal: RSC Advances

Doi: https://doi.org/10.1039/d1ra05138e

COVID-19 infection and nanomedicine applications for development of vaccines and therapeutics: An overview and future perspectives based on polymersomes

Authors: Mohammad A.I. Al-Hatamleh, Ma’mon M. Hatmal, Walhan Alshaer, Engku Nur Syafirah E.A. Rahman, Manali Haniti Mohd-Zahid, Dina M. Alhaj-Qasem, Chan Yean Yean, Iskandar Z. Alias, Juhana Jaafar, Khalid Ferji, Jean-Luc Six, Vuk Uskoković, Hiroshi Yabu, Rohimah 2021

Journal: European Journal of Pharmacology

Doi: https://doi.org/10.1016/j.ejphar.2021.173930

Curcumin-tannic acid-poloxamer nanoassemblies enhance curcumin’s uptake and bioactivity against cancer cells in vitro

Authors: Suhair Sunoqrot, Bayan Orainee, Dana A Alqudah, Fadwa Daoud, Walhan Alshaer2021

Journal: International Journal of Pharmaceutics

Doi: https://doi.org/10.1016/j.ijpharm.2021.121255

Design, Preparation, and Characterization of Effective Dermal and Transdermal Lipid Nanoparticles: A Review

Authors: Mohammad S. Mubarak Dima Khater, Hamdi Nsairat, Fadwa Odeh, Mais Saleh, Areej Jaber, Walhan Alshaer, Abeer Al Bawab2021

Journal: Cosmetics

Doi: https://www.mdpi.com/2079-9284/8/2/39#

Dielectric relaxation, XPS and structural studies of polyethylene oxide/iodine complex composite films

Authors: Ahmad Telfah, M-Ali Al-Akhras, Kholoud A Al-Izzy, Ahmad A Ahmad, Riad Ababneh, Mais Jamil A Ahmad, Carlos J Tavares, Roland Hergenröder2021

Journal: Polymer Bulletin

Doi: https://link.springer.com/article/10.1007/s00289-021-03593-1

Fabrication of aptamer-guided siRNA loaded lipopolyplexes for gene silencing of notch 1 in MDA-MB-231 triple negative breast cancer cell line

Authors: Lobna Gharaibeh, Walhan Alshaer, Suha Wehaibi, Rula Al Buqain, Dana A.Alqudah, Abdulfattah Al-Kadash, Hafsa Al-Azzawi, Abdalla Awidi, Yasser Bustanji2021

Journal: Journal of Drug Delivery Science and Technology

Doi: https://doi.org/10.1016/j.jddst.2021.102733

Gold nanoparticles ameliorate diabetic cardiomyopathy in streptozotocin-induced diabetic rats

Authors: Alaa AA Aljabali, Bahaa Al-Trad, Lina Al Gazo, Ghada Alomari, Mazhar Al Zoubi, Walhan Alshaer, Khalid Al-Batayneh, Bahja Kanan, Kaushik Pal, Murtaza M Tambuwala2021

Journal: Journal of Molecular Structure

Doi: https://doi.org/10.1016/j.molstruc.2021.130009

Investigating the association of CD36 gene polymorphisms (rs1761667 and rs1527483) with T2DM and dyslipidemia: Statistical analysis, machine learning based prediction, and meta-analysis

Authors: Ma’mon M. Hatmal, Walhan Alshaer, Ismail S. Mahmoud, Mohammad A. I. Al-Hatamleh, Hamzeh J. Al-Ameer, Omar Abuyaman, Malek Zihlif, Rohimah Mohamud, Mais Darras, Mohammad Al Shhab, Rand Abu-Raideh, Hilweh Ismail, Ali Al-Hamadi, Ali Abdelhay2021

Journal: Plos One

Doi: https://doi.org/10.1371/journal.pone.0257857

Lipid nanostructures for targeting brain cancer

Authors: Hamdi Nsairat, Dima Khater, Fadwa Odeh, Fedaa Al-Adaileh, Suma Al-Taher, Areej M. Jaber, Walhan Alshaer, Abeer Al Bawab, Mohammad S. Mubarak2021

Journal: Heliyon

Doi: https://www.cell.com/heliyon/fulltext/S2405-8440(21)02097-1

Loading of capsaicin-in-cyclodextrin inclusion complexes into PEGylated liposomes and the inhibitory effect on IL-8 production by MDA-MB-231 and A549 cancer cell lines

Authors: Hiba Abdelnabi, Walhan Alshaer, Hanan Azzam, Dana Alqudah, Ali Al-Samydai, Talal Aburjai2021

Journal: Zeitschrift für Naturforschung C

Doi: https://doi.org/10.1515/znc-2021-0018

Mapping the human genetic architecture of COVID-19

Authors: Mari EK Niemi, Juha Karjalainen, Rachel G Liao, Benjamin M Neale, Mark Daly, Andrea Ganna, Gita A Pathak, Shea J Andrews, Masahiro Kanai, Kumar Veerapen, Israel Fernandez-Cadenas, Eva C Schulte, Pasquale Striano, Minttu Marttila, Camelia Minica, Eirini Ma2021

Journal: Nature

Doi: https://www.nature.com/articles/s41586-021-03767-x

No impact of soluble epoxide hydrolase rs4149243, rs2234914 and rs751142 genetic variants on the development of type II diabetes and its hypertensive complication among Jordanian patients

Authors: Maysoon Khamees, Yazun Jarrar, Tariq Al-Qirim, Ismail Sami Mahmoud, Ma’mon M. Hatmal, Walhan Alshaer, Su-Jun Lee2021

Journal: International Journal of Clinical Practice

Doi: https://doi.org/10.1111/ijcp.14036

Optical characterizations of PMMA/metal oxide nanoparticles thin films: bandgap engineering using a novel derived model

Authors: Qais M Al-Bataineh, Ahmad A Ahmad, AM Alsaad, Ahmad D Telfah2021

Journal: Heliyon

Doi: https://www.cell.com/heliyon/fulltext/S2405-8440(21)00057-8

Optical, structural, and morphological characterizations of synthesized (Cd–Ni) co-doped ZnO thin films

Authors: AA Ahmad, AB Migdadi, AM Alsaad, Qais M Al-Bataineh, Ahmad Telfah2021

Journal: Applied Physics A

Doi: https://link.springer.com/article/10.1007/s00339-021-05090-8

Preparation, Characterization, and Anticancer Effects of Capsaicin-Loaded Nanoliposomes

Authors: Ali Al-Samydai, Walhan Alshaer, Emad A. S. Al-Dujaili, Hanan Azzam, Talal Aburjai2021

Journal: Nutrients

Doi: https://doi.org/10.3390/nu13113995

Preparation, Characterization, and Anticancer Effects of Capsaicin-Loaded Nanoliposomes.

Authors: A Al-Samydai, W Alshaer, EAS Al-Dujaili, H Azzam, T Aburjai2021

Journal: Nutrients

Doi: https://doi.org/10.3390/nu13113995

siRNA: Mechanism of action, challenges, and therapeutic approaches

Authors: Walhan Alshaer, Hadil Zureigat, Arwa Al Karaki, Abdulfattah Al-Kadash, Lobna Gharaibeh, Ma’mon M. Hatmal, Alaa A.A. Aljabali, Abdalla Awidi2021

Journal: European Journal of Pharmacology

Doi: https://doi.org/10.1016/j.ejphar.2021.174178

Stem Cell-Based Products in the Market

Authors: Alaa A. A. Aljabali, Khaled I. Seetan, Walhan Alshaer, Ejlal Abu-El-Rub, Mohammad A. Obeid, Dua Kamal, Murtaza M. Tambuwala2021

Journal: Advances in Application of Stem Cells: From Bench to Clinics

Doi: https://link.springer.com/chapter/10.1007/978-3-030-78101-9_11

Studies of composite films of polyethylene oxide doped with potassium hexachloroplatinate

Authors: M‐Ali AL‐Akhras, Shorooq E Alzoubi, Ahmad A Ahmad, Riad Ababneh, Ahmad Telfah2021

Journal: Journal of Applied Polymer Science

Doi: https://doi.org/10.1002/app.49757

Study of the effects of NCI667916 and NCI201725 on the invasion and migration of U87 cell line

Authors: Mutasem Taha Manar Zraikat, Walhan Alshaer, Tasneem Alshelleh, Ahmed M Sada Alhanjori, Diala Walid Abu-Hassan, Ghada O Tuffaha2021

Journal: Annals of the Romanian Society for Cell Biology

Doi: https://www.researchgate.net/profile/Manar-Alzraikat/publication/354968845_Study_of_the_effects_of_NCI667916_and_NCI201725_on_the_invasion_and_migration_of_U87_cell_line/links/615618c4a6fae644fbb4bb7d/Study-of-the-effects-of-NCI667916-and-NCI201725-on-the

Targeting siRNAs in cancer drug delivery

Authors: Mohammad A. Obeid, Alaa A.A. Aljabali, Walhan Alshaer, Nitin Bharat Charbe, Dinesh Kumar Chellappan, Kamal Dua, Saurabh Satija, Murtaza M. Tambuwalah2021

Journal: Advanced Drug Delivery Systems in the Management of Cancer

Doi: https://books.google.jo/books?hl=en&lr=&id=kiMZEAAAQBAJ&oi=fnd&pg=PP1&dq=info:sAtBFazWbaEJ:scholar.google.com&ots=5HlihTSxb-&sig=bo2E2DXO9euC9SqXsMg4XesEAKA&redir_esc=y#v=onepage&q&f=false

The role of TNFR2+ Tregs in COVID-19: An overview and a potential therapeutic strategy

Authors: Suhana Ahmad, Ma’mon M. Hatmal, Lidawani Lambuk, Mohammad A. I. Al-Hatamleh, Walhan Alshaer, Rohimah Mohamud2021

Journal: Life Sciences

Doi: https://doi.org/10.1016/j.lfs.2021.120063

A novel optical model of the experimental transmission spectra of nanocomposite PVC-PS hybrid thin films doped with silica nanoparticles

Authors: Qais M Al-Bataineh, AM Alsaad, AA Ahmad, Ahmad Telfah2020

Journal: Heliyon

Doi: https://www.cell.com/heliyon/fulltext/S2405-8440(20)31021-5

An potential MRI agent and an anticancer drug encapsulated within CPMV virus-like particles

Authors: Alaa AA Aljabali, Lorca Alzoubi, Yassmen Hamzat, Alaa Alqudah, Mohammad A Obeid, Mazhar S Al Zoubi, Raed M Ennab, Walhan Alshaer, Khaled Albatayneh, Bahaa Al-Trad, Dana A Alqudah, Dinesh Kumar Chellappan, Gaurav Gupta, Murtaza M Tambuwala, Dua Kamal, Davi2020

Journal: Combinatorial chemistry & high throughput screening

Doi: https://doi.org/10.2174/1386207323666200914110012

Anti-Oncogenic Activities Exhibited By Secretomes Of Mesenchymal Stem Cells Are Mediated By Modulation Of KITLG and DKK1 Genes In Glioma Stem Cells.

Authors: Nazneen Aslam, Elham Abusharieh, Duaa Abuarqoub, Dema Ali, Dana Al-Hattab, Suha Wehaibi, Ban Al-Kurdi, Fatima Jamali, Walhan Alshaer, Hanan Jafar, Abdalla S Awidi2020

Journal: Research square

Doi: DOI: https://doi.org/10.21203/rs.3.rs-38696/v1

Artificial Neural Networks Model for Predicting Type 2 Diabetes Mellitus Based on VDR Gene FokI Polymorphism, Lipid Profile and Demographic Data

Authors: Ma’mon M Hatmal, Salim M Abderrahman, Wajeha Nimer, Zaynab Al-Eisawi, Hamzeh J Al-Ameer, Mohammad AI Al-Hatamleh, Rohimah Mohamud, Walhan Alshaer2020

Journal: Biology

Doi: https://pubmed.ncbi.nlm.nih.gov/32823649/#:~:text=doi%3A%2010.3390/biology9080222.

Chemical Compositions and Anticancer Potential of`Essential Oil from Greenhouse-cultivated Ocimum basilicum Leaves

Authors: T. A. Aburjai, K. Mansi, Hanan Azzam, Dana A. Alqudah, W. Alshaer, and M. Abuirjei.2020

Journal: Indian Journal of Pharmaceutical Sciences

Doi: https://d1wqtxts1xzle7.cloudfront.net/106471798/chemical-compositions-and-anticancer-potential-ofessential-oil-from-greenhousecultivated-emocimum-basilicumem-leaves-libre.pdf?1696993141=&response-content-disposition=inline%3B+filename%3DChemical_Compositi

Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2

Authors: M.M. Hatmal, W. Alshaer, M.A.I. Al-Hatamleh, M. Hatmal, O. Smadi, M.O. Taha, A.J. Oweida, J.C. Boer, R. Mohamud, M. Plebanski2020

Journal: Cells

Doi: https://doi.org/10.3390/cells9122638

Enhancing chemosensitivity of wild-type and drug-resistant MDA-MB-231 triple-negative breast cancer cell line to doxorubicin by silencing of STAT 3, Notch-1, and β-catenin genes

Authors: Arwa Alkaraki, Walhan Alshaer, Suha Wehaibi, Lobna Gharaibeh, Duaa Abuarqoub, Dana A. Alqudah, Hafsa Al-Azzawi, Hadil Zureigat, Mamoun Souleiman, Abdalla. Awidi2020

Journal: Breast Cancer

Doi: https://link.springer.com/article/10.1007/s12282-020-01098-9

Fabrication of a novel nontoxic trichlorophenol-epichlorohydrin-based compound with high antimicrobial activity and thermal stability

Authors: F Mustafa, G Şanlıtürk, Mümtaz Güran, Fadwa Odeh, Walhan Alshaer, Rula Al Buqain, Mustafa Gazi2020

Journal: Journal of Environmental Science and Health, Part A

Doi: https://doi.org/10.1080/10934529.2020.1806633

Grafting of anti-nucleolin aptamer into preformed and remotely loaded liposomes through aptamer-cholesterol post-insertion

Authors: Hamdi Nsairat, Ismail S Mahmoud, Fadwa Odeh, Duaa Abuarqoub, Hafsa Al-Azzawi, Rand Zaza, Malak I Qadri, Said Ismail, Abeer Al Bawab, Abdalla Awidi, Walhan Alshaer2020

Journal: RSC Advances

Doi: https://doi.org/10.1039/D0RA07325C

Measurement and ab initio Investigation of Structural, Electronic, Optical, and Mechanical Properties of Sputtered Aluminum Nitride Thin Films

Authors: AM Alsaad, Qais M Al-Bataineh, IA Qattan, Ahmad A Ahmad, A Ababneh, Zaid Albataineh, Ihsan A Aljarrah, Ahmad Telfah2020

Journal: Frontiers in Physics

Doi: https://www.frontiersin.org/journals/physics/articles/10.3389/fphy.2020.00115/full

Microfluidics for pharmaceutical nanoparticle fabrication: The truth and the myth

Authors: Sherif I Hamdallah, Randa Zoqlam, Peer Erfle, Mark Blyth, Alaaldin M Alkilany, Andreas Dietzel, Sheng Qi2020

Journal: International journal of pharmaceutics

Doi: https://www.sciencedirect.com/science/article/pii/S0378517320303926

Notch 1 in cancer therapy: possible clinical implications and challenges

Authors: Lobna Gharaibeh, Nirmeen Elmadany, Kholoud Alwosaibai, Walhan. Alshaer2020

Journal: Molecular Pharmacology

Doi: https://molpharm.aspetjournals.org/content/98/5/559.abstract

Optical and structural properties of (PANI‐CSA‐PMMA)/NiNPs nanocomposites thin films for organic optical filters

Authors: Inshad Jum'h, Marwan S Mousa, Mahmoud Mhawish, Suhad Sbeih, Ahmad Telfah2020

Journal: Journal of Applied Polymer Science

Doi: https://onlinelibrary.wiley.com/doi/pdf/10.1002/app.48643

Optical band gap and refractive index dispersion parameters of boron-doped ZnO thin films: A novel derived mathematical model from the experimental transmission spectra

Authors: AM Alsaad, Qais M Al-Bataineh, AA Ahmad, Zaid Albataineh, Ahmad Telfah2020

Journal: Optik

Doi: https://www.sciencedirect.com/science/article/pii/S0030402620304757

Optical, structural, and crystal defects characterizations of dip synthesized (Fe-Ni) Co-doped ZnO thin films

Authors: Ahmad M Alsaad, Ahmad A Ahmad, Qais M Al-Bataineh, Areen A Bani-Salameh, Hadeel S Abdullah, Issam A Qattan, Zaid M Albataineh, Ahmad D Telfah2020

Journal: Materials

Doi: https://www.mdpi.com/1996-1944/13/7/1737

SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention

Authors: Ismail Mahmoud, Yazun Jarrar, Walhan Alshaer, Said Ismail2020

Journal: Biochimie

Doi: https://doi.org/10.1016/j.biochi.2020.05.012

Studying Antitumor Effects of siRNA Gene Silencing of Some Metabolic Genes in Pancreatic Ductal Adenocarcinoma

Authors: Ahmad Sada Al hanjori, Walhan Alshaer, Bayan Anati, Suha Wehaibi, Malek Zihlif2020

Journal: Current Molecular Pharmacology

Doi: https://doi.org/10.2174/1874467213666201012162250

Synthesis, Crystallography, Microstructure, Crystal Defects, Optical and Optoelectronic Properties of ZnO:CeO2 Mixed Oxide Thin Films

Authors: Qais M Al-Bataineh, Mahmoud Telfah, Ahmad A Ahmad, Ahmad M Alsaad, Issam A Qattan, Hakim Baaziz, Zoulikha Charifi, Ahmad Telfah2020

Journal: Photonics

Doi: https://www.mdpi.com/2304-6732/7/4/112

Alginate modified-PLGA nanoparticles entrapping amikacin and moxifloxacin as a novel host-directed therapy for multidrug-resistant tuberculosis

Authors: Sharif Abdelghany , Thaigarajan Parumasivam , Angel Pang , Ben Roediger , Patricia Tang , Kristina Jahn , Warwick John Britton , Hak-Kim Chan 2019

Journal: Journal of Drug Delivery Science and Technology

Doi: https://doi.org/10.1016/j.jddst.2019.05.025

Aptamer-guided nanomedicines for anticancer drug delivery

Authors: Walhan Alshaer, Hervé Hillaireau, Elias Fattal2019

Journal: Advanced Drug Delivery Reviews

Doi: https://www.sciencedirect.com/science/article/pii/S0169409X18302473

Aptamers chemistry: Chemical modifications and conjugation strategies

Authors: Fadwa Odeh, Hamdi Nsairat, Walhan Alshaer, Mohammad A Ismail, Ezaldeen Esawi, Baraa Qaqish, Abeer Al Bawab, Said I Ismail2019

Journal: Molecules

Doi: https://pmc.ncbi.nlm.nih.gov/articles/PMC6982925/#:~:text=doi%3A%2010.3390/molecules25010003

Association of Breastfeeding Duration with Susceptibility to Allergy, Influenza, and Methylation Status of TLR1 Gene

Authors: Ma’mon M. Hatmal, Nada N. Issa, Walhan Alshaer, Hamzeh J. Al-Ameer, Omar Abuyaman, Reema Tayyem, Nawal S. Hijjawi2019

Journal: Medicina

Doi: https://pmc.ncbi.nlm.nih.gov/articles/PMC6780093/#:~:text=doi%3A%2010.3390/medicina55090535

Co-encapsulation of thymoquinone with docetaxel enhances the encapsulation efficiency into PEGylated liposomes and the chemosensitivity of MCF7 breast cancer cells to docetaxel

Authors: Fadwa Odeh, Randa Naffa, Hanan Azzam, Ismail Mahmoud, Walhan Alshaer, Abeer Al Bawab, Said Ismail2019

Journal: Heliyon

Doi: https://www.cell.com/heliyon/fulltext/S2405-8440(19)36578-8

Developing and Characterization of Chemically modified RNA Aptamers for targeting Wild type and Mutated c-KIT Receptor Tyrosine Kinases

Authors: Ala'a Said Shraim, Abdelrahim Hunaiti, Abdalla Awidi, Walhan Alshaer, nidaa ababneh, Bashaer Abu-Irmaileh, Fadwa Odeh, Said Ismail2019

Journal: Journal of Medicinal Chemistry

Doi: https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.9b00868

Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: in vitro anti-proliferative and anti-invasive activity in glioblastoma

Authors: Alshaer Walhan, Zraikat Manar, Amer Amer, Nsairat Hamdi, Lafi Zainab, Dana, A. Alqudah, Al Qadi Enas, Alsheleh Tasneem, Odeh Fadwa, Alkaraki Arwa, Zihlif Malek, Bustanji Yasser, Fattal Elias, Abdalla Awidi2019

Journal: RSC Advances

Doi: https://doi.org/10.1039/C9RA05636J

Gold-coated plant virus as computed tomography imaging contrast agent

Authors: A. A. A. Aljabali, M. S. A. Zoubi, K. M. Al-Batanyeh, A. Al-Radaideh, M. A. Obeid, A. Al Sharabi, W. Alshaer, B. AbuFares, T. Al-Zanati, M. M. Tambuwala, N. Akbar, D. Evans2019

Journal: Beilstein J. Nanotechno

Doi: https://www.beilstein-journals.org/bjnano/articles/10/195

INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES

Authors: Ali Al-Samydai, Talal Aburjai, Walhan Alshaer, Hanan Azzam, Farah Al-Mamoori2019

Journal: INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES

Doi: https://d1wqtxts1xzle7.cloudfront.net/67398939/2545-libre.pdf?1621698626=&response-content-disposition=inline%3B+filename%3DQualitative_and_Quantitative_Analysis_of.pdf&Expires=1725173346&Signature=ZBeQkiRy44FXvWtkowowoQCtZMeFVl-muVq5WHM1nLIwAMfTuk13swgps

Ligand density on nanoparticles: A parameter with critical impact on nanomedicine

Authors: Alaaldin M Alkilany, Lin Zhu, Horst Weller, Alf Mews, Wolfgang J Parak, Matthias Barz, Neus Feliu2019

Journal: Advanced Drug Delivery Reviews

Doi: https://www.sciencedirect.com/science/article/pii/S0169409X19300602

Qualitative and quantitative analysis of capsaicin from Capsicum annum grown in Jordan

Authors: Ali Al-Samydai, Talal Aburjai, Walhan Alshaer, Hanan Azzam, Farah Al-Mamoori2019

Journal: Int. J. Res. Pharm. Sci

Doi: https://hero.epa.gov/hero/index.cfm/reference/details/reference_id/8113405

Remote loading of curcumin-in-modified β-cyclodextrins into liposomes using a transmembrane pH gradient

Authors: Fadwa Odeh, Hamdi Nsairat, Walhan Alshaer, Shrouq Alsotari, Rula Buqaien, Said Ismail, Abdalla Awidi, Abeer Al Bawab2019

Journal: RSC Advances

Doi: https://doi.org/10.1039/C9RA07560G

Screening the RFX6-DNA binding domain for potential genetic variants in patients with type 2 diabetes

Authors: Ismail Sami Mahmoud, Ayat Homsi, Hamzeh Al-Ameer, Jihad Alzyoud, Mais Darras, Mohammad Al Shhab, Malek Zihlif, Ma’mon Hatmal, Walhan Alshaer2019

Journal: World Journal of Diabetes

Doi: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422854/

The role of ligands in the chemical synthesis and applications of inorganic nanoparticles

Authors: Amelie Heuer-Jungemann, Neus Feliu, Ioanna Bakaimi, Majd Hamaly, Alaaldin Alkilany, Indranath Chakraborty, Atif Masood, Maria F Casula, Athanasia Kostopoulou, Eunkeu Oh, Kimihiro Susumu, Michael H Stewart, Igor L Medintz, Emmanuel Stratakis, Wolfgang J Pa2019

Journal: Chemical reviews

Doi: https://pubs.acs.org/doi/full/10.1021/acs.chemrev.8b00733

Antitumor activity of nanoliposomes encapsulating the novobiocin analogue 6BrCaQ in a triple-negative breast cancer model in mice

Authors: Juliette Vergnaud-Gauduchon Félix Sauvage, Elias Fattal, Walhan Al-Shaer, Stéphanie Denis, Emilie Brotinc, Christophe Denoyelle, Cécile Blanc-Fournier, Balthazar Toussainta, Samir Messaoudi, Mouad Alami, Gillian Barratt2018

Journal: Cancer Letters

Doi: https://doi.org/10.1016/j.canlet.2018.06.001

Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model

Authors: Walhan Alshaer, Hervé Hillaireau, Juliette Vergnaud, Simona Mura, Claudine Deloménie, Félix Sauvage, Said Ismail, Elias Fattal2018

Journal: Journal of Controlled Release

Doi: https://doi.org/10.1016/j.jconrel.2017.12.022

Confounding influence of tamoxifen in mouse models of Cre recombinase-induced gene activity or modulation

Authors: Seddik Hammad, Amnah Othman, Christoph Meyer, Ahmad Telfah, Joerg Lambert, Bedair Dewidar, Julia Werle, Zeribe Chike Nwosu, Abdo Mahli, Christof Dormann, Yan Gao, Kerry Gould, Mei Han, Xiaodong Yuan, Mikheil Gogiashvili, Roland Hergenröder, Claus Hellerbr2018

Journal: Archives of toxicology

Doi: https://pubmed.ncbi.nlm.nih.gov/29974145/#:~:text=8)%3A2549%2D2561.-,doi%3A%2010.1007/s00204%2D018%2D2254%2D4,-.

Optical and structural properties enhancement of hybrid nanocomposites thin films based on polyaniline doped with Zinc Oxide embedded in bimodal mesoporous silica (ZnO@SiOX) nanoparticles

Authors: Héla Chamroukhi, Zied Ben Hamed, A Telfah, M Bassou, A Zeinert, R Hergenröder, H Bouchriha2018

Journal: Optical Materials

Doi: https://www.sciencedirect.com/science/article/abs/pii/S0925346718305019

PO-440 Targeting of triple negative breast tumours using liposomes as drug delivery systems for sirna and hsp90 inhibitor

Authors: E Fatta J Vergnaud, H Hillaireau, F Sauvage, W Alshaer, S Denis, S Messaoudi, M Alami2018

Journal: ESMO Open

Doi: https://doi.org/10.1136/esmoopen-2018-EACR25.464

Synthesis of Gold Nanoparticles Using Leaf Extract of Ziziphus zizyphus and their Antimicrobial Activity

Authors: Alaa AA Aljabali, Yazan Akkam, Mazhar Salim Al Zoubi, Khalid M Al-Batayneh, Bahaa Al-Trad, Osama Abo Alrob, Alaaldin M Alkilany, Mourad Benamara, David J Evans2018

Journal: Nanomaterials

Doi: https://www.mdpi.com/2079-4991/8/3/174

Therapeutic Aptamers in Discovery, Preclinical and Clinical Stages

Authors: Said Ismail, Walhan Alshaer2018

Journal: Advanced Drug Delivery Reviews

Doi: https://www.sciencedirect.com/science/article/pii/S0169409X18302011

Selected standard protocols for the synthesis, phase transfer, and characterization of inorganic colloidal nanoparticles

Authors: Jonas Hühn, Carolina Carrillo-Carrion, Mahmoud G Soliman, Christian Pfeiffer, Daniel Valdeperez, Atif Masood, Indranath Chakraborty, Lin Zhu, Marta Gallego, Zhao Yue, Monica Carril, Neus Feliu, Alberto Escudero, Alaaldin M Alkilany, Beatriz Pelaz, Pablo 2017

Journal: Chemistry of Materials

Doi: https://pubs.acs.org/doi/abs/10.1021/acs.chemmater.6b04738

Selection and targeting of EpCAM protein by ssDNA aptamer

Authors: Walhan Alshaer, Nida Ababneh, Mamon Hatmal, Heba Izmirli, Moujab Choukeife, Alaa Shraim, Nour Sharar, Aya Abu-Shiekah, Fadwa Odeh, Abeer Al Bawab, Abdalla Awidi, Said Ismail2017

Journal: PLoS One

Doi: https://doi.org/10.1371/journal.pone.0189558

Protein corona: opportunities and challenges

Authors: Saeid Zanganeh, Ryan Spitler, Mohsen Erfanzadeh, Alaaldin M Alkilany, Morteza Mahmoudi2016

Journal: The international journal of biochemistry & cell biology

Doi: https://www.sciencedirect.com/science/article/pii/S135727251630005X

Functionalizing liposomes with anti-CD44 aptamer for selective targeting of cancer cells

Authors: Walhan Alshaer, Hervé Hillaireau, Juliette Vergnaud, Said Ismail, Elias Fattal2015

Journal: Bioconjugate chemistry

Doi: https://pubs.acs.org/doi/abs/10.1021/bc5004313

Looking into Living Cell Systems: Planar Waveguide Microfluidic NMR Detector for in Vitro Metabolomics of Tumor Spheroids

Authors: Ayten Kalfe, Ahmad Telfah, Jörg Lambert, Roland Hergenröder2015

Journal: Analytical chemistry

Doi: https://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b01603

Colloidal stability of citrate and mercaptoacetic acid capped gold nanoparticles upon lyophilization: effect of capping ligand attachment and type of cryoprotectants

Authors: Alaaldin M Alkilany, Samer R Abulateefeh, Kayla K Mills, Alaa I Bani Yaseen, Majd A Hamaly, Hatim S Alkhatib, Khaled M Aiedeh, John W Stone2014

Journal: Langmuir

Doi: https://pubs.acs.org/doi/abs/10.1021/la504000v

Aptamers: promising molecules for cancer stem cell targeting

Authors: SI Ismail, W Alshaer, N Ababneh, E Fattal2013

Journal: J Mol Genet Med

Doi: https://www.researchgate.net/profile/Walhan-Alshaer/publication/285667700_Aptamers_promising_molecules_for_cancer_stem_cell_targeting/links/5772fead08ae07e45db24836/Aptamers-promising-molecules-for-cancer-stem-cell-targeting.pdf

Exocytosis of nanoparticles from cells: role in cellular retention and toxicity

Authors: Ramin Sakhtianchi, Rodney F Minchin, Ki-Bum Lee, Alaaldin M Alkilany, Vahid Serpooshan, Morteza Mahmoudi2013

Journal: Advances in colloid and interface science

Doi: https://www.sciencedirect.com/science/article/pii/S0001868613001280

In Vitro Selection of Modified RNA Aptamers Against CD44 Cancer Stem Cell Marker

Authors: Nidaa Ababneh, Walhan Alshaer, Omar Al-Louzi, Azmi Mahafzah, Mohammed El-Khateeb, Hervé Hillaireau, Magali Noiray, Elias Fattal, Said Ismail2013

Journal: Nucleic acid therapeutics

Doi: https://doi.org/10.1089/nat.2013.0423

Nanoparticle–protein interactions: a thermodynamic and kinetic study of the adsorption of bovine serum albumin to gold nanoparticle surfaces

Authors: Stefano P Boulos, Tyler A Davis, Jie An Yang, Samuel E Lohse, Alaaldin M Alkilany, Lisa A Holland, Catherine J Murphy2013

Journal: Langmuir

Doi: https://pubs.acs.org/doi/abs/10.1021/la402920f

The gold standard: gold nanoparticle libraries to understand the nano–bio interface

Authors: Alaaldin M Alkilany, Samuel E Lohse, Catherine J Murphy2013

Journal: Accounts of chemical research

Doi: https://pubs.acs.org/doi/abs/10.1021/ar300015b

Gold nanorods: their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions

Authors: Alaaldin M Alkilany, Lucas B Thompson, Stefano P Boulos, Patrick N Sisco, Catherine J Murphy2012

Journal: Advanced drug delivery reviews

Doi: https://www.sciencedirect.com/science/article/pii/S0169409X11000500

Gold nanorod crystal growth: From seed-mediated synthesis to nanoscale sculpting

Authors: Catherine J Murphy, Lucas B Thompson, Davin J Chernak, Jie An Yang, Sean T Sivapalan, Stefano P Boulos, Jingyu Huang, Alaaldin M Alkilany, Patrick N Sisco2011

Journal: Current Opinion in Colloid & Interface Science

Doi: https://www.sciencedirect.com/science/article/abs/pii/S1359029411000045

Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway

Authors: S Chandra, MJ Romero, A Shatanawi, AM Alkilany, Ruth B Caldwell, R William Caldwell2011

Journal: British journal of pharmacology

Doi: https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1476-5381.2011.01584.x

The many faces of gold nanorods

Authors: Catherine J Murphy, Lucas B Thompson, Alaaldin M Alkilany, Patrick N Sisco, Stefano P Boulos, Sean T Sivapalan, Jie An Yang, Davin J Chernak, Jingyu Huang2010

Journal: The Journal of Physical Chemistry Letters

Doi: https://pubs.acs.org/doi/abs/10.1021/jz100992x

Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?

Authors: Alaaldin M Alkilany, Catherine J Murphy2010

Journal: Journal of nanoparticle research

Doi: https://link.springer.com/article/10.1007/s11051-010-9911-8

Cellular uptake and cytotoxicity of gold nanorods: molecular origin of cytotoxicity and surface effects

Authors: Alaaldin M Alkilany, Pratik K Nagaria, Cole R Hexel, Timothy J Shaw, Catherine J Murphy, Michael D Wyatt2009

Journal: small

Doi: https://onlinelibrary.wiley.com/doi/full/10.1002/smll.200801546

Chemical sensing and imaging with metallic nanorods

Authors: Catherine J Murphy, Anand M Gole, Simona E Hunyadi, John W Stone, Patrick N Sisco, Alaaldin Alkilany, Brian E Kinard, Patrick Hankins2008

Journal: Chemical Communications

Doi: https://pubs.rsc.org/en/content/articlelanding/2008/cc/b711069c/unauth

Gold nanoparticles in biology: beyond toxicity to cellular imaging

Authors: Catherine J Murphy, Anand M Gole, John W Stone, Patrick N Sisco, Alaaldin M Alkilany, Edie C Goldsmith, Sarah C Baxter2008

Journal: Accounts of chemical research

Doi: https://pubs.acs.org/doi/abs/10.1021/ar800035u

Optical constants of polyaniline/poly (methylmethacrylate) blend

Authors: HA Al-Attar, A Dh Telfah2004

Journal: Optics communications

Doi: https://doi.org/10.1016/j.optcom.2003.10.018

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