​The Podium talk was presented by Prof. Rula Darwish at the First Pan-Arab and the Second Jordanian Women Physicians Conference (Amman, Jordan). This presentation delves into the current status of antibiotic resistance, highlighting its significant public health implications. It reviews the global burden of resistance, the limitations of existing antibiotics, and the emergence of multidrug-resistant pathogens. Emphasis is placed on the need for innovative strategies, including the development of novel antibiotics, alternative therapies, and enhanced antimicrobial stewardship. The discussion also explores whether current efforts are sufficient or if additional measures and resources are essential to address this escalating crisis. Solutions are framed within the context of sustainable global health initiatives and policy reform.​​