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Pharmaceutical Applications of Supercritical Fluid Technology (SFTPharm)

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Featured Publications

Solvent-free method for masking the bitter taste of azithromycin dihydrate using supercritical fluid technology

Authors: Hadeia Mashaqbeh 1, Rana M Obaidat 2, Mo'tasem M Alsmadi 32024

Journal: Drug Dev Ind Pharm.

Doi: https://doi.org/10.1080/03639045.2023.2298892

The In Vitro, In Vivo, and PBPK Evaluation of a Novel Lung-Targeted Cardiac-Safe Hydroxychloroquine Inhalation Aerogel

Authors: Mo'tasem M Alsmadi 1 2, Mays M Jaradat 3, Rana M Obaidat 4, Mohammad Alnaief 5, Rabab Tayyem 6, Nasir Idkaidek 72023

Journal: AAPS PharmSciTech

Doi: https://doi.org/10.1208/s12249-023-02627-3

Enhancing Atorvastatin In Vivo Oral Bioavailability in the Presence of Inflammatory Bowel Disease and Irritable Bowel Syndrome Using Supercritical Fluid Technology Guided by wbPBPK Modeling in Rat and Human

Authors: Mo'tasem M Alsmadi 1, Nour M Al-Daoud 2, Rana M Obaidat 2, Niazy A Abu-Farsakh 32022

Journal: AAPS PharmSciTech

Doi: https://doi.org/10.1208/s12249-022-02302-z

Development and Evaluation of Cocoa Butter Taste Masked Ibuprofen Using Supercritical Carbon Dioxide

Authors: Rana Obaidat 1, Haneen Aleih 2, Hadeia Mashaqbeh 2, Bashar Altaani 2, Mo'tasem M Alsmadi 2, Mohammad Alnaief 32021

Journal: AAPS PharmSciTech

Doi: https://doi.org/10.1208/s12249-021-01962-7

Development, In Vitro Characterization, and In Vivo Toxicity Evaluation of Chitosan-Alginate Nanoporous Carriers Loaded with Cisplatin for Lung Cancer Treatment

Authors: Mo'tasem M Alsmadi 1, Rana M Obaidat 2, Mohammad Alnaief 3, Borhan Aldeen Albiss 4, Nabil Hailat 52020

Journal: AAPS PharmSciTech

Doi: https://doi.org/10.1208/s12249-020-01735-8

Enhancement of dissolution of atorvastatin through preparation of polymeric solid dispersions using supercritical fluid technology

Authors: Bashar Altaani,* Rana Obaidat, and Walaa Malkawi2020

Journal: Res Pharm Sci

Doi: https://doi.org/10.4103%2F1735-5362.283812

Preparation of Hybrid Alginate-Chitosan Aerogel as Potential Carriers for Pulmonary Drug Delivery

Authors: Mohammad Alnaief ,,Rana M. Obaidat ,and Mo’tasem M. Alsmadi Mo’tasem M. Alsmadi SciProfilesScilitPreprints.orgGoogle Scholar 22020

Journal: Polymers

Doi: https://doi.org/10.3390/polym12102223

A Comparative Solubility Enhancement Study of Cefixime Trihydrate Using Different Dispersion Techniques

Authors: Rana M Obaidat 1, Mai Khanfar 2, Rand Ghanma 22019

Journal: AAPS PharmSciTech

Doi: https://doi.org/10.1208/s12249-019-1395-y

Loading and evaluation of meloxicam and atorvastatin in carrageenan microspherical aerogels particles

Authors: Mohammad Alnaief, Rana Obaidat, Hadeia Mashaqbeh 2019

Journal: J Appl Pharm Sci

Doi: https://dx.doi.org/10.7324/JAPS.2019.90112

Solubility enhancement of nimodipine through preparation of Soluplus® dispersions

Authors: Rawda Yaseen AlSheyyab, Rana Mohammad Obaidat, Yara Radi Altall, Rana Talal Abuhuwaij, Rand Radwan Ghanma, Anoud Sameer Ailabouni, Hadeia Ahmad Mashaqbeh, Shayma Al-Haj 2019

Journal: J Appl Pharm Sci

Doi: https://dx.doi.org/10.7324/JAPS.2019.90905

Effect of processing parameters on preparation of carrageenan aerogel microparticles

Authors: Mohammad Alnaief 1, Rana Obaidat 2, Hadeia Mashaqbeh 22018

Journal: Carbohydr Polym

Doi: https://doi.org/10.1016/j.carbpol.2017.10.038

Experimental and Computational Comparative Study of the Supercritical Fluid Technology (SFT) and Kneading Method in Preparing β-Cyclodextrin Complexes with Two Essential Oils (Linalool and Carvacrol)

Authors: Nizar A Al-Shar'i 1, Rana M Obaida2018

Journal: AAPS PharmSciTech

Doi: https://doi.org/10.1208/s12249-017-0915-x

Investigation of Carrageenan Aerogel Microparticles as a Potential Drug Carrier

Authors: Rana M Obaidat 1, Mohammad Alnaief 2, Hadeia Mashaqbeh 32018

Journal: AAPS PharmSciTech

Doi: https://doi.org/10.1208/s12249-018-1021-4

Investigation of Carrageenan Aerogel Microparticles as a Potential Drug Carrier

Authors: Rana M Obaidat ,Mohammad Alnaief,Hadeia Mashaqbeh2018

Journal: AAPS PharmSciTech

Doi: http://dx.doi.org/10.1208/s12249-018-1021-4

Preparation and Preliminary Characterization of Hybrid Alginate - Carrageenan Aerogel: Effect of Gelation Methods

Authors: Alnaief M, Mohammad BT, Aljarrah M, Obaidat R.2018

Journal: Jordanian Journal of Physics

Doi: https://www.researchgate.net/publication/332413927_Preparation_and_Preliminary_Characterization_of_Hybrid_Alginate_-_Carrageenan_Aerogel_Effect_of_Gelation_Methods

Significant solubility of carbon dioxide in Soluplus® facilitates impregnation of ibuprofen using supercritical fluid technology

Authors: Rana Obaidat 1, Mohammed Alnaief 2, Philip Jaeger 32018

Journal: Pharm Dev Technol

Doi: https://doi.org/10.1080/10837450.2017.1315135

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