At the 2nd Dubai Medical Research Forum (DMRF 2025), Dubai, UAE, Dr. Mohammad Obeid participated through a poster presentation entitled “Personalised Medicine through siRNA Delivery: The Promise of Microfluidic Niosomes.” His participation focused on showcasing how microfluidic technology can enable the reproducible fabrication of niosome-based nanocarriers optimized for siRNA delivery, supporting the advancement of personalised medicine. 

The objective of the work was to develop scalable and highly controllable microfluidic methods for producing siRNA-loaded niosomes with suitable size, stability, and delivery efficiency. The methodology involved microfluidic mixing of non-ionic surfactants and cholesterol under controlled flow-rate ratios and total flow rates to generate uniform nanoparticles, followed by evaluation of their physicochemical properties, stability, and nucleic acid encapsulation potential. 

The key findings, consistent with Dr. Obeid’s published work, showed that microfluidic processing produces smaller, more homogenous, and more stable niosomes compared to conventional methods, with strong potential for efficient nucleic-acid delivery and clinical translation. The outcome of this participation included stimulating discussions on integrating microfluidics into personalised nanomedicine manufacturing pipelines and opening opportunities for future interdisciplinary collaborations in RNA therapeutics and advanced drug delivery systems. 

For deeper insight into the scientific basis of this work, see Dr. Obeid’s related peer-reviewed publications on microfluidic niosome fabrication and nucleic acid delivery, such as his study on solvent effects in microfluidic niosome preparation (International Journal of Pharmaceutics X, 2023): https://pubmed.ncbi.nlm.nih.gov/36852395

and his work on microfluidic niosome characterisation