The 104th General Session of the International Association for Dental Research, held jointly with the 55th AADOCR and 50th CADR Annual Meetings, convenes March 25–28, 2026 in San Diego, USA. This flagship forum showcases cutting-edge advances across dental, oral, and craniofacial research—spanning biomaterials, cariology, periodontics, prosthodontics, endodontics, craniofacial biology, public health, digital dentistry, and AI. The program features plenary lectures, symposia, hands-on workshops, poster sessions, junior investigator competitions, and industry exhibitions highlighting emerging technologies and translational pathways. With a global, multidisciplinary audience of researchers, clinicians, educators, and industry partners, the meeting emphasizes rigorous methods, reproducibility, and clinical impact, while providing extensive opportunities for networking, collaboration development, and trainee mentorship. Special focus areas include precision dentistry, minimally invasive and regenerative approaches, data-driven diagnostics, and implementation science to accelerate evidence uptake in practice and education. This meeting serves as a premier venue for disseminating new findings, shaping research agendas, and fostering international partnerships that advance oral health worldwide.